The Evaluation of Serum Pseudocholinesterase

نویسنده

  • M. G. Khan
چکیده

DESPITE numerous tests used in the diagnosis of liver disease, in manv cases it is still difficult to decide whether there is liver damage, and if so, how much. This study was done to evaluate serum pseudocholinesterase estimation as a routine test of liver function, and to conmpare it with certain commonly used tests, viz., serum bilirubin, zinc sulphate flocculation test, thymol turbidity test, alkaline phosphatase, and blood transanminase levels. Also to show if it is of anv value in distinguishing between intrahepatic and extrahepatic jaundice.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Grand mal seizure in a child 30 minutes after Cyclogyl (cyclopentolate hydrochloride) and 10% Neo-Synephrine (phenylephrine hydrochloride) eye drops were instilled.

A grand mal seizure is an unexpected, rare adverse event in a child receiving eye drops to dilate the pupils for an eye examination. A case is reported of a convulsion in a 23-month-old boy after he received Cyclogyl (cyclopentolate) and Neo-Synephrine (phenylephrine) eye drops before ophthalmoscopy. His serum sodium was 125 mEq/L, and he had low plasma pseudocholinesterase activity. Children e...

متن کامل

The effects of azidothymidine therapy on pseudocholinesterase concentrations in asymptomatic HIV-positive patients.

The purpose of this study was to determine if a correlation exists between long-term azidothymidine (AZT) therapy and low pseudocholinesterase concentrations in patients who are infected with the human immunodeficiency virus (HIV). A pilot study was conducted of 10 patients infected with HIV, 5 of whom were receiving AZT. Laboratory tests, including complete blood count (CBC), liver function te...

متن کامل

The silent gene for serum pseudocholinesterase.

The investigations of human serum pseudocholinestrase (acylcholine acylhydrolase) (International Union of Biochemistry, . i96i: 3.I.I.8) suggest the existence of four allelic genes controlling the formation of different enzyme types: gene Elu for usual esterase, Ela for atypical (dibucaine resistant) esterase, El' for a fluoride-resistant type, and Els for a 'silent' gene. The four genes result...

متن کامل

Pseudocholinesterase activity in thyroid disease.

The present evidence indicates that serum pseudocholinesterase activity is increased to about 20% above the normal level in thyrotoxicosis and decreased by about 30% in myxoedema. Treatment restores the esterase level to the average mean activity of random normal as the patient becomes euthyroid. There is no evidence in the present investigation that any of the pseudocholinesterase variants mod...

متن کامل

Evaluation of the UV-340 spectrophotometric determination for pseudocholinesterase activity (EC 3.1.1.8) in human serum.

A pseudocholinesterase catalytic activity assay using p-hydroxybenzoylcholine as substrate and measuring the decrease of NADPH at 340 nm was compared with a colorimetric method using acetylthiocholine as substrate. The assay is simple, uses 50 microliters serum and is performed at 37 degrees C. Precision of the UV-340 method was good except at low ranges. The catalytic activity was depressed by...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Ulster Medical Journal

دوره 31  شماره 

صفحات  -

تاریخ انتشار 1962